BDBM412533 US10399972, Example 24::{3,9-difluoro-8-[(1S,4S)-2-oxa-5- azabicyclo[2.2.1]hept-5-yl]-5,11- dihydro-6H-pyrido[2,3- b][1,5]benzodiazepin-6-yl}[trans- 4-(propan-2- yloxy)cyclohexyl]methanone
SMILES CC(C)O[C@H]1CC[C@@H](CC1)C(=O)N1Cc2cc(F)cnc2Nc2cc(F)c(cc12)N1C[C@@H]2C[C@H]1CO2
InChI Key InChIKey=CHNWNUVCJSDKKR-FIRPJDEBSA-N
Data 2 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 1 hit for monomerid = 412533
TargetIsocitrate dehydrogenase [NADP] cytoplasmic(Homo sapiens (Human))
China Pharmaceutical University
Curated by ChEMBL
China Pharmaceutical University
Curated by ChEMBL
Affinity DataIC50: <10nMAssay Description:Inhibition of IDH1 RI32C mutant (unknown origin) by kinase-Glo luminescent assayMore data for this Ligand-Target Pair
Ligand Info